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ATP6AP1 associates with the V 0 sector of lysosomal v-ATPase, and its loss impairs lysosomal acidification v-ATPases are present in multiple cellular locations as proton pumps, such as the plasma membrane, Golgi-derived and secretory vesicles, endosomes and lysosomes 27

Safety and pharmacokinetics of chimeric anti-Shiga toxin 1 and anti-Shiga toxin 2 monoclonal antibodies in healthy volunteers

doi: 10.1074/jbc.M112.413872 nder , Humphrey PT, McOmber B, et al

BPC-157 enhances cell migration through the FAK-paxillin pathway, essentially improving the cellular GPS system that guides repair cells toward damaged tissue

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The fact that we did not observe an antiviral effect in the lower respiratory tract underscores the need of further treatment optimization before its potential evaluation in humans