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myl7:EGFP) , which carried pathogenic LMNA variants that had been previously isolated and reported to cause EDMD 29

Serum obtained was frozen at 80C until used to measure biochemical parameters [Albumin, Aspartato amino transferase (AST), -hydroxybutyrate (BHB), Total bilirubin, Ceruloplasmin, Creatine Kinase (CK), Creatinine, Triglycerides, Non Esterified Fatty Acids (NEFA), Total cholesterol, High density Lipoprotein (HDL), Low density Lipoprotein (LDL), Gamma glutamyl transpeptidase (GGT), Glucose, Insulin, Protein, Urea, Ca, Mg, and Zn] using clinical chemistry and turbidimetry analyzer Biosystems BA400 (Biosystems S.A., Barcelona, Spain) according to Girldez et al

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