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Cellular Trojan horse initiates bimetallic Fe-Cu MOF-mediated synergistic cuproptosis and ferroptosis against Malignancies

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To evaluate sorbitol-induced cell death, treated fibroblasts and MNPs were fixed with 4% paraformaldehyde and permeabilized with saponin, as described above

Evidence from a Molecular Pharmaceutics study shows acetate counterions can become part of peptide aggregates, so the acid plays a real role in solution behavior, but at the diluted concentrations used in reconstitution it primarily serves to keep the peptide clear and in solution

Mustafa AM, Shaheen AM, Zaki HF, Rabie MA

It can be costly and complex but can be combined with IF for improved detection, as demonstrated by combining DAPI + and CD45 + staining with a CEP8 probe, and utilizing convolutional neural networks (CNNs) for analysis [123]