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-Gal A cleaves the terminal galactose from globotriaosylceramide (Gb3), deficiency of -Gal A leads to progressive accumulation of Gb3 and its analogue lyso-Gb3 (globotriaosylsphingosine) within lysosomes in most cell types, thus affecting different tissues and organs [173,174]

Neuroimmunomodulation 2011

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