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The initiation dose is always given intravenously at around 6mg/kg, thereafter it is switched to a SC formulation at 90mg 12-weekly or 8-weekly[95]

Because the body cannot produce B12, it must be obtained through diet or supplementation

This sub-study within TILDA investigates the association of folate and vitamin B 12 (wave 1) with incident depression at later recruitment waves

Natural Food Sources of Vitamin B12 While supplementation is often necessary for those with deficiencies or absorption challenges, its also helpful to know where you can find B12 in your diet: Beef liver and organ meats Sardines and mackerel Clams and shellfish Eggs Milk, yogurt, and cheese Fortified cereals and plant-based milks (especially important for vegetarians and vegans) These foods are a great foundation, but if youre still struggling with symptoms, professional evaluation is key

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This gives them a very large circumference, though it may not feel so squishy because its underneath the muscle layer