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Metallothionein has a strong metal ion binding capacity, is able to reduce metal ion-induced neurotoxicity, and thus may play an important role in the treatment of diseases such as Alzheimers disease and Parkinsons disease [7,55]

The averages of the spatial percentage change were 5.713% in the upper part and 5.412% in the lower part

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Collaborative efforts across basic, translational, and clinical research will be essential to fully harness the potential of ferroptosis as a cornerstone of next-generation glioblastoma therapy, ultimately improving outcomes for patients facing this devastating disease