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In addition to the adverse reactions listed above which have been observed in patients treated with cefditoren pivoxil, the following adverse reactions and altered laboratory test results have been reported for cephalosporin class antibiotics: Adverse Reactions: Allergic reactions, anaphylaxis, drug fever, Stevens-Johnson syndrome, serum sickness-like reaction, erythema multiforme, toxic epidermal necrolysis, colitis, renal dysfunction, toxic nephropathy, reversible hyperactivity, hypertonia, hepatic dysfunction including cholestasis, aplastic anemia, hemolytic anemia, hemorrhage, and superinfection

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When it is released by the endothelial cells that line the blood vessels, NO prompts the surrounding smooth muscles to relax, causing vasodilation and thereby lowering blood pressure.[13] Lower NO levels are associated with the development of high blood pressure, heart disease, and ED.[14] Unfortunately, NO production declines with age

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