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Int J Dev Biol 55:467476 Zlokovic BV (2008) The blood-brain barrier in health and chronic neurodegenerative disorders

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In addition, CL-bromelain was reported for its suppression of ERK, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase (145)

The ethanolic extract of BM at the dose of 200 mg/kg showed a good hepatoprotective effect in nitrobenzene-induced liver damage in mice model by an increase in SOD, CAT and GPx enzymes and by normalizing the serum marker enzymes such as aspartate transaminase, alanine transaminase, and alkaline phosphatase

Stress is a critical player in CYP3A, CYP2C, and CYP2D regulation: role of adrenergic receptor signaling pathways

Along with this, cerebrovascular accident (CVA) is currently the second leading cause of death in the Western world, ranking after heart disease and before cancer[337], and experts predict that it is likely to be soon the most common cause of death worldwide[338]