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NPT100-18A interacts with the C-terminal domain of -syn, displaces it from the membrane, reducing the formation of -syn oligomers, and subsequently reduced neuronal accumulation of -syn and decreased markers of cell toxicity

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Behavioral assessments, including climbing pole, rotarod, and open field tests, were performed by experimenters blinded to the group assignments

Galasso C, Gentile A, Orefice I, Ianora A, Bruno A, Noonan DM, et al

Si se est utilizando, seguir de cerca para determinar la eficacia clnica del diazepam y ajustar la dosificacin segn sea necesario