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Since NAPQI amounts are so much higher than mercury values, it would be expected that NAPQI might significantly reduce the capacity of hair proteins to bind mercury if the binding capacity of the hair sulfhydryl groups was exceeded by the previous binding of NAPQI

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U., & Lee, S

This research group demonstrated that in HEK293T cells and THP-1 monocytes treated with TNFa the artificially reduced expression of Set7/9 was concomitant with the down-regulation of NFkB-dependent pro-inflammatory genes (such as CCL2 (MCP-1), TNF (TNFa), CXCL8 (IL-8) etc.)

10.3390/ijms22052609 211 WangH