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in Encyclopedia of Nanotechnology (ed Bhushan, B.) 32643277 (Springer Netherlands, Dordrecht, 2016)

Conventional epigenetic drugs, such as HDAC inhibitors or DNMTi, broadly alter chromatin states and often exhibit substantial off-target effects, limiting their suitability for treating depression or addiction in a targeted manner 196

A biopsy is often performed to confirm the diagnosis, as histopathology can reveal key features of the condition, such as interface dermatitis and vacuolar changes in the skin cells

10.1038/srep24873 Sci