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2011 Demonstrated neuroprotective effects in traumatic brain injury and peripheral nerve damage models with improved recovery markers

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Extracellular matrix and collagen research Beyond the wound-healing context, GHK-Cu is used in research on extracellular matrix biology more generally including collagen synthesis, the cross-linking reactions catalyzed by lysyl oxidase, the deposition and remodeling of matrix in various cell-culture systems, and the broader matrix metabolism that connects to tissue mechanics and tissue function

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Third, independent replication outside the original group has been limited , although a 2025 paper in Biogerontology by Al-Dulaimi and colleagues represents a recent independent confirmation of the in vitro telomere effect