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Long-term estrogen therapy without a progestogen in women with a uterus is associated with an elevated risk of endometrial neoplasia

NADPH oxidase exerts a B cell-intrinsic contribution to lupus risk by modulating endosomal TLR signals

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These long-term exposures have been associated with a variety of systemic effects (mycotoxicoses) in both humans and animals and most commonly manifest as nephrotoxicity, hepatotoxicity, immunosuppression, carcinogenicity, and teratogenicity

DFP, as a more conservative iron chelator with milder iron binding affinity than DFO (Cabantchik et al., 2013), is smaller and considerably more lipophilic than DFO, which allows it to cross cell membranes and penetrate into subcellular organelles, making it one of a few iron chelators that can effectively cross the BBB and access CNS iron pools (Marchand et al., 2022)

Journal of Dietary Supplements, 13 (3), 269-282