Because it targets collagen, elastin, and glycosaminoglycans, GHK-Cu is particularly relevant for patients concerned about fine lines and early photoaging
Role of FK506 binding protein 12 in morphine-induced mu-opioid receptor internalization and desensitization
Am J Physiol Cell Physiol 306:C745-752
Safety profile in research models: Does not significantly affect IGF-1 or glucose metabolism, which simplifies experimental interpretation
Onderzoeksgebieden Binnen een laboratoriumcontext wordt GHK-Cu onder meer ingezet als modelverbinding in de volgende onderzoeksrichtingen: Modellen rond collageen- en elastine-synthese in dermale fibroblast-culturen Onderzoek naar gen-expressie van extracellulaire-matrix-componenten (ECM-remodellering) in vitro Cordinatiechemie van koper(II)-tripeptiden en modellen voor koperion-transport Modellen rond oxidatieve balans en cellulaire stressrespons Topische formulering-, stabiliteits- en permeatie-onderzoek met een waterige serumbasis Referentie- en modelverbinding voor koper-tripeptide-chemie GHK-Cu vergeleken met verwante verbindingen GHK-Cu is verkrijgbaar in verschillende onderzoeksvormen, wat het handig maakt om formuleringen en toedieningsroutes naast elkaar te modelleren
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