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In mixed inflammatory cholangitis it is therefore recommended to initiate antibiotic therapy first and, if there is no significant improvement within 1-2 weeks, administer prednisolone at anti-inflammatory doses, additionally

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Rarely, allergic reactions such as itching, swelling, or increased irritation may occur

Besides contributing to PCOS-associated hyperandrogenism, insulin resistance is also linked the development of impaired glucose tolerance and type 2 diabetes mellitus [48], in both obese and non-obese women with PCOS [49]

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*Polycystic ovarian syndrome (PCOS) is characterised by women often having irregular or no menstruation