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doi:10.1073/pnas.96.14.8150

Susa ST, Preuss CV (2022) Drug metabolism

Further research is warranted to explore how other specific pathways implicated in PF pathogenesis, such as the PI3K/Akt signaling pathway, WNT/-catenin signaling pathway, JAK/STAT signaling pathway, and AMPK signaling pathway, interact with ferroptosis in regulating the development of PF

Like L-arginine, taking L-citrulline supplements may also offer possible benefits, such as: That said, its important to note that more research is needed to fully support and understand the possible benefits of taking L-citrulline and L-arginine supplements

Reduced activity of complex IV was observed only in sporadic PD patients (Moon and Paek 2015)

The decentralized clinical trial (DCT) model is an advancement in the clinical trial design, as well as a support and a development of the CNS trials challenges