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doi: 10.1039/D1RA00328C

G., Sullivan, P

The antimicrobial activity of the cathelicidin Ll37 is inhibited by f-actin bundles and restored by gelsolin

Interestingly, initial data suggest that the Ctr effector TmeA might activate N-WASP like EspF U does which would imply that Cpn has evolved a completely different mechanism for F-actin polymerisation and branching, possibly as an adaptation to the different target tissues involved ( Cpn : lung epithelia

The tTG is the autoantigen in CD, 12,13 while mTG, a heavily consumed processed food additive, is described as a potential driver in CD 66,94,134,224229 and systemic autoimmunity