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CT associated with psychosis risk includes abuse (physical, sexual, and emotional), neglect (physical or psychological) [4, 14, 128, 149, 150], active and/or passive peer victimization (in particular bullying) [14, 149, 151], and exposure to the familial disrupted environment, including parental separation or death [6, 14, 149], incarcerated family member, the witness of domestic violence [125], developmental challenges associated with foster care [152], and parental communication deviance that has been confirmed as a risk factor irrespective of familial genetic susceptibility [105]

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30 In the context of PCOS, PAK2 has been implicated in regulating KGN cell apoptosis and proliferation via the -catenin/c-Myc/PKM2 signaling pathway

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