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Drug-specific surface functionalization has been employed for RIF, and further functionalization with poly(ethylene imine) (PEI) yields high loading and controlled drug delivery to MTB-infected macrophages compared to uncoated MSNP

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Pre-medication and Side Effect Management To minimize infusion-related reactions, patients typically receive: Acetaminophen Antihistamines Sometimes corticosteroids before infusions Adequate hydration before, during, and after infusions helps reduce the risk of headaches and other reactions

Additionally, pQCT data suggested that the increase in cortical BMC observed may be attributed to an increase in the cross-sectional area of the bones