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To assess the effect of amino acids on TC1-6 cells, cells were cultured in MEM (Gibco, 11090-081) supplemented with 5% FBS, 1% Penicillin/Streptomycin, 4 mM glutamine and 4 mM alanine

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Insulin-like growth factor-1, as discussed earlier, has implications on lipid and glucose metabolism [87, 88], and its exogenous administration enhances insulin sensitivity in healthy adults [139, 140] as well as those with T2D [155]

Mary Armonios of the Johns Hopkins Kimmel Cancer Center, maintaining normal telomere length is inversely correlated with immune system abnormalities, and a 2013 review notes that melatonin modulates immune responses by helping to proliferate immunocompetent cells and secrete immune mediators.18 19 Tumor suppression The telomere-lengthening, along with the attendant increase in immune function, may help ward off cancer as well

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