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A decline in the dendritic spine density (DSD) is an early characteristic feature of many neurodegenerative diseases (Fiala et al., 2002

In epilepsy, the GABAergic system can malfunction, meaning the brain doesnt have enough inhibition to counterbalance excitation

A few can eventually reduce to very low doses (1 to 2 mg daily) that provide just enough GLP-1/GIP activation to prevent the hormonal rebound that drives weight regain

This helps raise the baseline energy threshold, potentially reducing the severity and duration of crashes following physical or cognitive exertion

Recognition and management of methemoglobinemia and hemolysis in a G6PD-deficient patient on experimental anticancer drug Triapine

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