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rigorous human evidence is limited and individual results vary

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Across GLP-1 trials, about 60% of lost weight returns within the first year and roughly 75% returns over the longer curve, with the fastest regain in the early months. In semaglutides extension, about two-thirds returned within one year. The pattern reflects removal of appetite suppression after major weight loss

This is just for the simple fact that bags can go missing during flights and you dont want to lose all your diabetes supplies