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Consequently, NRF2 dissociates from Keap1, escapes ubiquitination and degradation, accumulates in the cytoplasm, and ultimately translocates to the nucleus [85, 91, 92]

Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice

The script was deposited on GitHub and made publicly available ( Statistical analysis of obtained light/heavy (L/H) ratios for each cysteine (resembling ratios of reduced to oxidized cysteine residues) was performed in Perseus

10.1021/acs.chemrev.7b00205 Chem

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