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However, many of these articles primarily provide descriptive overviews of phytochemicals or focus predominantly on preclinical mechanistic findings without systematically integrating translational, clinical, pharmacokinetic, and safety dimensions within a single framework

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Polysulfidation at this residue, or its mutation to serine, abolishes persulfide dioxygenase activity [43]

Compared to sorafenib, sintilimab plus a bevacizumab biosimilar (Sint-IBI305) showed the greatest OS benefit (HR=0.57, 95% CI=0.430.75, P score=0.944), followed by camrelizumab plus rivoceranib (Cam-Rivo

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