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Immunofluorescent stainings For staining of tissue sections, human and murine lung tissue was fixed in 4% formalin prior to paraffin embedding

Previous studies on global SUMOylation have focused on the dynamic nature of this modification playing roles during development, and associations between SUMOylation and neurodegeneration gaining traction however roles for SUMOylation in the central nervous system during the process of human aging remain understudied[117, 118]

BSE resulted in a 0.2 mmol/L reduction in fasting blood glucose compared to placebo (95% confidence interval -0.44 to -0.01, p=0.04), which did not meet the predefined outcome of 0.3 mmol/L

In addition, its result revealed that smoking in combination with GSTM1 (two-way) and GSTT, GSTP (three-way) genes might increase the risk of CAD

Toxicology 328 , 1220 (2015)

The authors consider central hypothyroidism (suboptimal TSH production) to be extremely rare, limited to cases of obvious HP disease or damage (~1 in 100,000 persons)