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Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance

Exclusive enteral nutrition (EEN) with intake of liquid elemental, semi-elemental, or polymeric formulas for 68 weeks has been shown to be effective in Crohns disease (CD)

Louis, MO: CV Mosby

It modulates the activity of inflammatory cytokines and helps maintain the balance between pro-inflammatory and anti-inflammatory signals

10.3390/medsci6020033 35

This leads to the activation of downstream signaling pathways that include the mitogen-activated protein kinase (MAPK), PI3K/AKT and STAT pathways, which mediate Met-dependent cell proliferation, survival, migration and invasion (Figure 2)