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While many people tolerate creatine well on an empty stomach, certain groups may want to avoid this approach: People with sensitive digestive systems: If you have IBS, frequent stomach upset, or generally sensitive digestion, taking creatine with food may be gentler on your system

Loose skin has lost the strength and support of the collagen network that exists at the deepest layers of the skin

Avoid prolonged or excessive use without medical supervision

It is used to disrupt the production of collagen, a key factor in the formation of Peyronie's disease scar tissue

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As L-Carnitine is responsible for transporting fatty acids to the mitochondria for oxidation and energy production, increasing its daily intake thus prevents the body from accumulating fat