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Stability: This modification gives IGF-1 LR3 a significantly longer half-life, approximately 20 to 30 hours, compared to natural IGF-1, which typically lasts only 1215 minutes in circulation

Before mixing: The lyophilized vial can stay at room temperature or in the refrigerator

Critically, AOD-9604 did not produce the metabolic side effects associated with full-length growth hormone, including no insulin resistance or glucose intolerance, no elevation of IGF-1 levels, no fluid retention or joint pain, and no cardiovascular parameter changes

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Clones were verified by Sanger sequencing (Fig

The main effect of these drugs is to reduce inflammation, whether its from arthritis, asthma or some other condition