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Description

confirmed that the up-regulation of Drp1 induced by high glucose promoted the release of hexokinase-II from mitochondria, which subsequently inhibited the PINK1/Parkin pathway of mitophagy, leading to retinal damage in DR

It is the most abundant thiol-containing antioxidant in the human body and exists in both a reduced and oxidized state in cells, with over 95% of GSH existing in its reduced state [1]

-methyl aromatic amino acids are LAT1 specific, and 18F-labeled 3-fluoro-l--methyl-tyrosine (FAMT) has been used as LAT1 specific probe for cancer detection