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Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, et al

Zhang, Avni P

In addition, inflammation and the pathophysiology of DN involve complex signaling pathway activation (Bui et al., 2020), such as NF-B pathway, The janus kinase/signal transducers and activators of transcription (JAKSTAT) pathway and nod-like receptor (NLR) family pyrin domain containing 3 (NLRP3) inflammasome pathway

In some rare cases, this has resulted in fingers, toes or arms, needing to be amputated, he said

Peng Y, Zhao Y, Chen Y, Yang Z, Zhang L, Xiao W, Yang J, Guo L, Wu Y

This is an important effect because it increases the survival rate of neurons, which could be used in treating neurodegenerative diseases such as Alzheimer's and Parkinson's disease