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More help Relationships Between Two Key Events (Including MIEs and AOs) This table summarizes all of the KERs of the AOP and is populated in the AOP-Wiki as KERs are added to the AOP.Each table entry acts as a link to the individual KER description page

Permanent opening of the mPTP results in mitochondrial depolarization, inhibition of respiration, cessation of ATP synthesis, mobilization of cytochrome C, and apoptosis 43

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