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The proton nuclear magnetic resonance ( 1 H NMR, 400 MHz, D 2 O) spectra exhibited signals at H 2.21 (quartet, 2H, H-3), 2.59 (triplet of doublets, 2H, H-4), 2.98 (doublet of doublets, 2H, CH 2 S), 3.86 (triplet, 1H, H-2), 4.02 (singlet, 2H, H-10), and 4.60 (triplet, 1H, H-7)

MicroRNA miR-212-5p, found at low levels in extracellular vesicles from injured brain tissues in TBI mice, has been identified as a negative regulator of PTGS2a key mediator of ferroptotic signalingsuggesting that miR-212-5p may confer neuroprotection by suppressing ferroptosis (227)

Louis, MO, USA) as well as a single control incubated with the reducing agent -mercaptoethanol (Thermo Scientific, Stockholm, Sweden)

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Intramuscular injection of artemether was more neurotoxic than that of artesunate in a mouse model, suggesting differences in the optimal dosing of different derivatives (Nontprasert et al., 1998

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