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Mutagenesis Valproate was not mutagenic in an in vitro bacterial assay (Ames test), did not produce dominant lethal effects in mice, and did not increase chromosome aberration frequency in an in vivo cytogenetic study in rats

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doi: 10.3389/fimmu.2022.1049936 Received 21 September 2022 Accepted 07 November 2022 Published 21 November 2022 Volume 13 - 2022 Edited by Zhihao Jia, Purdue University, United States Reviewed by Jingbo Pang, University of Illinois at Chicago, United States