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Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations

these results are consistent with the activation of PPAR and inhibition of NF-B resulting in suppression of COX-2 29,30

2.2 Isolation of exosomes Firstly small EVs were isolated by differential centrifugation

When too much Fe 2+ iron accumulates in the cell, it accelerates the creation of ROS via Fenton reaction that stimulates lipid peroxidation and causing ferroptosis (Zhang et al

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J Biol Chem 1997;272:92216.Google Scholar Harrison, MD, Jones, CE, Dameron, CT