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Subsequent investigations revealed that c9,t11-CLA effectively suppresses the expression of pro-inflammatory factors, chemokines, and ICAM-1 by inhibiting NF-B transcriptional regulation and dampening MAPK signaling pathway activity, thus exhibiting potent anti-inflammatory properties

Ramos Gonzlez EJ, Ramirez Jirano LJ, Garca Martnez DZ et al (2018) Estudio comparativo de melatonina contra los tratamientos inmunomoduladores (interfern beta y acetato de glatirmero) en un modelo murino de esclerosis mltiple