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All disease begins in the Gut: was Hippocrates right

In addition, the inclusion of gp42 may have shielded the immune system from neutralizing epitopes on gH/gL that preferentially neutralize EBV infection of epithelial cells such as CL40

Alterations in microbial composition (dysbiosis) can compromise regulatory T cell (Treg) function, disrupt intestinal barrier integrity, and promote systemic inflammation