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It is the most common enzymatic disorder of red blood cells

Poling LL, Cocozziello D, He M, Hurh E, Lobbardi R, Jackson KL, et al

However, antimony resistance has made the use of substitute drugs necessary, particularly in the Indian subcontinent

To clarify whether the first N-terminal residues of BNIP3 represent the discrete structural unit that directly can activate BAX, we conducted an established in vitro BAX activity assay utilising BNIP3-peptide 1-49, other BH3-only BAX activators (BIM and PUMA) as positive controls 38 , and bovine serum albumin and the antiapoptotic BCL XL as negative controls 2

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