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Biochem Eng J 41(3):234240

Myocardial fibrosis is an important feature of cardiac remodeling in DCM ( 2 -terminal Jun kinase (JNK), Janus kinase, and signal transducer and activator of transcription (JAK-STAT) pathways, further leading to impaired cardiac structure and function ( 2 and NOX 4

Besides, consistently higher paracetamol regimen may minimize all problems related to possible variations from animal to animal and from time to time in a given animal and invariably link paracetamol action with seizures, severely damaged brain tissue, hepatomegaly, fatty liver and necrosis, breakdown of liver function with profoundly increased ammonia, AST and ALT levels