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Xia H, Wu Y, Zhao J, Cheng C, Lin J, Yang Y, et al

Opioids are metabolized mainly in the liver through two major enzyme systems, cytochromes P450 (CYP450) (particularly CYP3A2, CPY3A4 and CYP2C8) and UDP-glucuronosyltransferases, to produce morphine 3-glucuronide and to a lesser extent, morphine 6-glucuronide, morphine 3-sulfate and normorphine [20,21]

Cest surtout aprs 40 50 ans que la production endogne de GSH a des risques de ne plus suffire

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The muscles, livers, and hepatopancreases (brown shrimp) were macerated and 0.250.35 g of tissue was taken for weighing and homogenization