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Reszko clarifies

To provide support for this idea we show 1) that the CTD can bind directly to the catalytic core in-trans to inhibit PLC activity, and 2) restricting interactions of the CTD with the catalytic core through removal of the flexible linker strongly increased PLC activity that was not further activated by G proteins

The perimeter technique is similar to the 2-bladed square procedure [17]

Patients presenting with abdominal and pelvic pain across two or more distinct locations now have a dedicated code

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