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Rothe K, et al

Nicotinamide mononucleotide attenuates ischemia-reperfusion injury induced by donor liver from cardiac death through Sirt3

In many patients with IC/PBS, these signaling pathways are found to be either dysfunctional or interrupted at some point during the diseases progression ( FIC, which is broadly recognized as the natural animal equivalent of IC/PBS in humans, demonstrates similar pathological characteristics