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Given the close association between insulin resistance and hepatic fat deposition, polyphenols offer significant therapeutic value in addressing metabolic dysfunction in NAFLD

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Efficacy and safety of lipid lowering by alirocumab in chronic kidney disease

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For instance, the addition of ganitumab, a monoclonal antibody targeting IGF-1R, to carboplatin/paclitaxel chemotherapy in patients with primary epithelial ovarian cancer did not improve progression-free survival in a phase II multicenter controlled trial (65), despite the promising results of IGF-1R inhibition in various preclinical studies (25, 32, 64)

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Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid

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