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By binding to GLP-1 receptors in the hypothalamus, they reduce appetite and promote satiety, leading to significant weight reduction in clinical trialswith newer agents achieving approximately 15% weight loss in obesity without diabetes (semaglutide) and up to 21% (tirzepatide), with somewhat lower reductions typically seen in patients with type 2 diabetes

doi:10.1016/j.jcmg.2022.04.014 Bhatt DL, Steg PG, Miller M, et al

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Most clinics provide specific guidance on activity progression

Well talk about your health goals, answer your questions, and see if this treatment could support your wellness journey