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CR and DL have distinct effects on mTORC1 signaling and autophagy mTORC1 signaling has been extensively studied in the brains from AD mouse models, revealing mTORC1 activation in these brains 25,26

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This regulation is associated with reduced oxidative stress, attenuated glial activation, and stabilization of transcriptional and neurovascular homeostasis

T follicular B helper T (Tfh) cells are distinguished from other Teff cells by their unique role in memory B cell development and plasma cell maturation (26)

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