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65 The recurrence of symptoms in young patients with asymptomatic periods should raise suspicion for BRIC

doi: 10.1007/s11010-005-1095-7

In addition, patients with STK11/LKB1 mutations were resistant to PD-1 inhibitors in KRAS-mutant LAC, suggesting a new mechanism of resistance 103

4 Carcinogenic mechanisms of microbiota Unlike normal cells, tumor cells could coexist with specific bacteria and fungi, forming a symbiotic microbiota that benefits both tumor and microbial proliferation and drug resistance ( Aspergillus, Blastomyces, Cryptococcus, Malassezia, Candida, Bacillus , while bacteria such as Staphylococcus, Streptococcus, Pseudomonas aeruginosa (P

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