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Moreover, Cyt c release triggers the production of mtROS, suggesting a role of mtROS in redox signaling 51

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We therefore quantified mRNA expressions of the enzymes involved in BA synthesis (Fig

It is suggested that this leads to an increase in the synthesis of cysteine and then the antioxidant glutathione, and thus represents a physiological feedback mechanism for limiting oxidative stress

Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism