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Description

Further epigenetic evaluation revealed reductions in three histones (H3Ac, H4Ac, H3K4me3) that transcriptionally activate insulin-2 gene promoters and significant elevation in two histones (H3K9me3, H3K20me3) that suppress/silence these promoters [172]

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doi: 10.1093/ecco-jcc/jjad073 173 NordmannAJSuter-ZimmermannKBucherHCShaiITuttleKREstruchRet al

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