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Upon exposure to 808 nm NIR laser irradiation, the photosensitizer ICG generates a substantial amount of reactive ROS, inhibiting the excessive proliferation of P

Although their activity on a single target may be lower compared to single-target drugs, the synergistic effects of multi-target modulation result in a total effect greater than the sum of the individual effects, leading to better efficacy and fewer adverse reactions

The first changes after PRF treatment are seen within couple of weeks

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Furthermore, although substantial evidence supports the association between pathological hyperprolactinemia and adverse metabolic outcomes, current research suggests that the relationship between prolactin and metabolic risk is not a simple linear model