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Metabolic and melanocortin gene expression alterations in male offspring of obese mice

This function is analogous to that of ceruloplasmin in the circulation and brain: both HEPH and ceruloplasmin ensure that cellular iron release does not lead to toxic ferrous accumulation

doi: 10.1111/jpi.12736 85 MadiganA

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These include genetic testing for variants in the MTHFR and other genes that affect methylation pathways, as well as blood testing for homocysteine levels

The incidences of type 2 diabetes mellitus, hypertriglyceridemia, hypercholesterolemia, and hypertension decreased from 32.6%, 37.7%, 33.4%, and 44.9% (pre-IGB) to 21.3%, 17.4%, 18.9%, and 34.8% respectively at 12 months post IGB removal