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Excessive androgens enhance the activity of T suppressor cells or promote Th1 responses, and Th1-mediated autoimmunity, resulting in thyroid cytolysis and hypothyroidism (68)

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Clinically, mitochondrial dysfunction symptoms include: dysautonomia (orthostasis, heat intolerance, POTS-like symptoms) muscle rigidity or tremors variable energy levels cognitive fog heightened reactivity to stress worsening symptoms during infection or inflammation poor exercise tolerance These same patterns appear in Parkinsons disease, neurodegenerative disorders, dysautonomia, and trauma-linked hyperarousal

The Combined Effect of GST Polymorphisms and Risk of CAD To further assess the existence of an interaction between the studied GST genes, the combination of their polymorphisms was investigated

Zhang Y, Zhao S, Fu Y, et al